The News Review:
- Gene Variation Is ‘Major Genetic Determinant f Psoriasis’
- Study IDs pulmonary fibrosis target
- MAKImd Restoration Medicine pens Merritt Island ffice
- Some Brain Tumors May Be Mediated By Tiny Filament n Cells
- Radiation Testing Concerns
- HEALTH NEWS : Heat humidity and health
Gene Variation Is ‘Major Genetic Determinant f Psoriasis’
Science Daily (press release)
13 issue of PLoS Genetics researchers in the U School of Medicine’s Department of Dermatology confirm that the presence of HLA-Cw*0602 a gene variation or allele on chromosome 6 found to be associated with psoriasis by numerous investigators is the "major genetic determinant" of psoriasis but that other nearby genetic variations also play an independent role in contributing to the disease"The HLA-Cw*0602 gene variation stands alone as a high risk for psoriasis" said Gerald G. professor of dermatology Benning Presidential Endowed Chair holder and a co-author on the study. "A major question has been: are there other genetic variations in this region that associate with psoriasis?"The study reported in PLoS Genetics identifies two other genetic variations on chromosome 6 that also have significant association with psoriasis.
Related from Acnemonster: More than skin deep
Study IDs pulmonary fibrosis target
United Press International
The researchers says targeting of the gene NX4 utilizes genetic and pharmacologic strategies that were successful in treating pulmonary fibrosis in mice and will be developed for future testing in humans. “We’ve identified the target. We know the enemy now” said Dr. Subramaniam Pennathur an assistant professor of internal medicine and a member of the research team. “This is the first study that shows pulmonary fibrosis is driven by this NX4 enzyme. But what’s really significant is this discovery may have relevance to fibrosis in other organ systems not just the lung. Pennathur said people suffering from common cardiac or kidney diseases that often involve fibrosis also might benefit from treatments stemming from the research.
MAKImd Restoration Medicine pens Merritt Island ffice
Space Coast Medicine and Healthy Living
?MAKImd Restoration Medicine is a unique medical practice that deals with the issues of aging with an approach that realizes that not all issues may be medical in nature? said Dr. ?The Makimd team uses a multi-faceted method of dealing with the physical and medical issues associated with slowing the aging process ? as well as addressing the mental and emotional aspects of aging. spacecoastmedicine.
Some Brain Tumors May Be Mediated By Tiny Filament n Cells
Science Daily (press release)
(See related UCSF news release. )The findings both reported online on August 23 2009 in "Nature Medicine" are the first direct evidence of a role of primary cilia in cancer which the researchers say could lead to a new strategy for diagnosing subtypes of cancers and to potential targets for therapy. "These findings are very exciting" says the senior of the medulloblastoma study Arturo Alvarez-Buylla PhD UCSF Heather and Melanie Muss Professor of Neurological Surgery and a member of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF. "In the last few years primary cilia have been shown to be essential for the cell-signaling that drives both human development including the differentiation of stem cells into neurons and some diseases including polycystic kidney disease. The fact that the two UCSF studies implicate primary cilia in two totally different tissues suggests the finding is likely to be very general. "Significantly in both UCSF studies the findings in mice revealed that primary cilia had opposing roles in cancers depending on which mutated genes initiated the aberrant cell-signaling events to begin with.
Radiation Testing Concerns
Newsinferno.com
locations said the AP and was conducted to determine the amount of radiation Americans receive from medical imaging some of which are considered unnecessary or not proven as valuable. The LATimesBlog noted that the research was just reported in the New England Journal of Medicine and included Dr. Reza Fazel of the Emory University School of Medicine and colleagues. CT scans and heart perfusion scanning are considered the two main issues said the LATimes. CT scans provide three-dimensional imaging via X-ray technology and heart perfusion scanning utilizes an injectable radioactive element to enable measurement of blood flow through arteries to the heart the LATimes explained. The Wall Street Journal blog pointed out that about four million adults in the U.
HEALTH NEWS : Heat humidity and health
Greene County Record
Bowyer FNPGreene Family Medicine Published: August 27 2009The dog days of summer are hopefully nearing an end. However as we all know summers in Central Virginia are quite fickle: bright blue skies soft breeze with low humidity and a pleasant mid 80’s stretch one week and then hot humid muggy sticky grey mid 90 degree days the following week! Change is a constant and does keep life interesting but with heat index change it is very important to realize extreme heat can be quite serious and sometimes deadly. Heat related deaths and illnesses are preventable yet each year people in our country die from excessive heat exposure. People at most risk are the elderly the very young people with mental illness and people with chronic diseases. Nevertheless even young hale and hearty individuals can experience heat related illness and even death if they participate in vigorous and demanding physical activity during hot weather and don’t take proper precautions.
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