The News Review:
- New Therapeutic Target Could Help Patients With Pulmonary Fibrosis
- Some Brain Tumors May Be Mediated By Tiny Filament n Cells
- Why the Health Care Debate Is So Explosive
- Cilias dual role in cancer
- Healing touch big medicine
New Therapeutic Target Could Help Patients With Pulmonary Fibrosis
Science Daily (press release) (press release)
The treatments attack an oxidant-generating enzyme NX4 that researchers discovered is involved in the fibrotic process — which involves scar-like tissue formation in an organ such as the lung. The researchers’ findings will be published in the September issue of the journal Nature Medicine. "We’ve identified the target. We know the enemy now" said Subramaniam Pennathur M.
Some Brain Tumors May Be Mediated By Tiny Filament n Cells
Science Daily (press release)
(See related UCSF news release. )The findings both reported online on August 23 2009 in "Nature Medicine" are the first direct evidence of a role of primary cilia in cancer which the researchers say could lead to a new strategy for diagnosing subtypes of cancers and to potential targets for therapy. "These findings are very exciting" says the senior of the medulloblastoma study Arturo Alvarez-Buylla PhD UCSF Heather and Melanie Muss Professor of Neurological Surgery and a member of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF. "In the last few years primary cilia have been shown to be essential for the cell-signaling that drives both human development including the differentiation of stem cells into neurons and some diseases including polycystic kidney disease. The fact that the two UCSF studies implicate primary cilia in two totally different tissues suggests the finding is likely to be very general. "Significantly in both UCSF studies the findings in mice revealed that primary cilia had opposing roles in cancers depending on which mutated genes initiated the aberrant cell-signaling events to begin with.
Why the Health Care Debate Is So Explosive
” The death panels are just the latest in a long line of monsters that seems to speak to a generation’s anxieties – not just for health care but for the nation itself. Democrats always – always every single time – get taken by surprise. Their full page newspaper ads during the Truman years were to say the least defensive: “The President’s Plan is NT socialized medicine. ” But the fears are real and can be answered – not by dismissal or denials or disdain – but by hopes and dreams that go as deep as people’s anxieties. Finally as if all that were not enough the battle for health reform invariably becomes a battle for political control. Harry Truman’s famous come-from-behind 1948 election victory prominently featured national health insurance. The first square-off during the 1960 election campaign saw the candidates Vice President Richard Nixon and Sen.
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Cilias dual role in cancer
Primary cilia are specialised appendages that extend from the surface of many cell types and have been implicated in cell signalling. They are crucial during foetal development for signalling pathways mediated by a protein known as Hedgehog. As Hedgehog has also been implicated in cancers Jeremy Reiter Arturo Alvarez-Buylla and their respective colleagues explored the possible contribution of primary cilia to tumour formation. Studying two types of cancer basal cell carcinoma and medulloblastoma the two groups independently found that cilia could favour or inhibit tumour formation in mice.
Healing touch big medicine
“They thought I was selling out because I also believed in our Western medicine. I kept saying there’s a balance here of both worlds and that’s going to make the difference” adding “Now those ideas don’t seem so farfetched. ” Even though mainstream medicine has come around to at least recognizing the possibilities of natural remedies the major pharmaceutical companies have been slow to respond. According to Greeson “Big Pharma doesn’t want to listen until you’ve got something tangible. We’ve tried to make some contacts with them but they haven’t been too receptive. ur function is more educational of raising awareness but getting plants in a lab while a separate entity does go hand in hand with what we’re doing. ” Toward that end Greeson revealed that two of the plants her team brought back from Madagascar have recently shown promise as potential anti-cancer drugs.