The News Review:
- Researchers hail the attack of the fat-eating cells
- Weir takes his medicine as wacky pen rolls on
- Slade: Health care reform must focus on prevention good medicine
- Natural Treatments for Common Ailments
- Cause of fat tissue inflammation in metabolic syndrome patients …
- Insights Into Failed HIV-1 Vaccine Trial
- Why HIV Progresses Faster In Women Than In Men With Same Viral Load
Researchers hail the attack of the fat-eating cells
This newly discovered immune defence against weight gain is overwhelmed by chronic overeating but can be "rebooted" by a readily available drug that could offer a less invasive alternative to bariatric or stomach-stapling surgery. In a groundbreaking paper published online yesterday in the journal Nature Medicine the researchers also suggest a reason that obesity can lead to Type 2 diabetes. "This really targets where the problem lies so this is very exciting to us" says Dr. Hans-Michael Dosch the paper’s senior author. The immune system’s critical role in obesity and diabetes and the likelihood it can be reprogrammed to reverse these epidemic conditions came as a shock to the paper’s researchers says Dosch a senior scientist at the Hospital for Sick Children. Researchers at the University of Toronto Mount Sinai Hospital and Stanford University in California also conducted the study.
Weir takes his medicine as wacky pen rolls on
Globe and Mail
The players are often their own referees. So Weir will continue his third round this morning five shots rather than four behind the leader. Given his nature he’s probably fired up to go and make a run at the leaders. Fans have been filing into the Canadian Golf Hall of Fame and Museum on the property to see an exhibition of his memorabilia. He’ll be inducted into the Hall later this year. It would be pretty neat for him to win the tournament in the year he’s inducted and in its 100th playing. Weir said he was “comfortable with the ruling although he was surprised to be called back in to the rules trailer a day after the original decision.
Slade: Health care reform must focus on prevention good medicine
Re-examine employer-based health care. Employer-based health insurance has failed us. It bankrupted General Motors bankrupted the city of Columbia and forces unrelated to the nature of entrepreneurship and business manipulate its structure. Not only can the onset of a life-threatening disease by an employee cause health care costs to rise for an entire company and its employees but also the premature birth of an employee’s child or the brain injury of a careless youth. What capriciousness created a system that makes unrelated people and businesses the victims of other unrelated people’s misfortune carelessness or neglect? Why should a car dealer or a university or a manufacturer have to worry about this?We must insist that our government and legislators town city county state and nation re-examine the premise’s upon which our patchwork of health care systems are built and how the poor minorities and rural populations are disproportionately impacted by this broken system. Though there are real dangers of jumping from the frying pan into the fire we must act; doing nothing is not an option. Dean Slade is the director of grants and planning at Eau Claire Cooperative Health Centers and the designer of “The Plan” a comprehensive primary health care model with 350 members partially funded by a grant from the United Way of the Midlands which provides access to primary health care services for individuals and employers for an application fee of $20 and $25 per month.
Natural Treatments for Common Ailments
She looked into Mother Nature’s medicine cabinet on “The Early Show Saturday Edition” noting the surprising healing power of herbal remedies. They could be just what the doctor ordered. PAIN RELIEF Mild headaches: Tiger balm. Chinese ointment contains menthol and can ease pain when rubbed into neck or temples. Arthritis pain: Turmeric fish oil.
Cause of fat tissue inflammation in metabolic syndrome patients …
Mainichi Daily News
Experiments on mice had already shown that such inflammation diminishes the effects of insulin leading to such conditions as hardened arteries and diabetes. However the underlying mechanism causing the inflammation had been a mystery. A research team led by Ryozo Nagai a professor at the University of Tokyo’s Graduate School of Medicine compared obese mice that were fed a high-fat diet with mice that were fed a regular diet. The obese mice were found to have heightened levels of CD8+ T cells which fight pathogens before a rise in macrophages. Researchers then studied mice with decreased T-cell levels as well as mice they created without such cells and found that these animals did not experience inflammation in visceral fat tissue despite their high-fat diet. Furthermore it was discovered that visceral fat inflammation could be controlled and the effects of insulin improved in mice suffering from inflammation by removing their CD8+ T cells. Ichiro Manabe an associate professor at the University of Tokyo explained “As T cells are crucial to the immune system it is difficult to remove all of them.
Related from Weightlossmonster: Weight Loss Surgery Effective Treatment for Teen Metabolic Syndrome
Insights Into Failed HIV-1 Vaccine Trial
Science Daily (press release)
"ur findings demonstrate that there is no correlation between Ad5 neutralizing antibodies and T-cell immune responses" explains Barouch who is Chief of the Division of Vaccine Research at BIDMC and Associate Professor of Medicine at Harvard Medical School. "Moreover subjects with baseline Ad5-specific neutralizing antibodies did not develop higher levels of Ad5-specific T-cell responses as compared with subjects without baseline Ad5-specific neutralizing antibodies. "The Ad5 virus is a weakened form of adenovirus which is responsible for the common cold and is extremely widespread in the general population. In the Merck vaccine candidate Ad5 was used as a vector to transport three HIV-1 genes a strategy that helps to overcome limitations posed by the HIV-1 virus.
Why HIV Progresses Faster In Women Than In Men With Same Viral Load
Science Daily (press release)
"This study may help to account for reported gender differences in HIV-1 disease progression by demonstrating that women and men differ in the way their immune systems respond to the virus" says Marcus Altfeld MD PhD of the Ragon Institute and the MGH Division of Infectious Disease the study’s senior author. "Focusing on immune activation separately from viral replication might give us new therapeutic approaches to limiting HIV-1-induced pathology. "It has become apparent in recent years that HIV-1-infected patients with a high level of immune activation progress to AIDS more rapidly. Why this happens is an area of intense investigation.