The News Review:
- Novel technique developed at CHP may lead to HIV vaccine
- Controversy doesn’t derail stem cell progress
- Summer yoga opportunities in the Black Hills allow participants to …
- Personalized Cancer Treatment of the Future: RNAi Gene Silencers
- Inhibiting key protein may restore the balance between bone …
- Framingham Heart Study follows the beat in new directions
- Health utcomes Driving New Hospital Design
Novel technique developed at CHP may lead to HIV vaccine
place_ad_here(“half”); Posted on Mon May. 18 2009 Novel technique developed at CHP may lead to HIV vaccine By Josh GoldsteinInquirer Staff Writer A novel approach that involves inserting genetic material into muscle might lead to a long-sought HIV vaccine according to a study led by the chief scientific officer at Children’s Hospital of Philadelphia published yesterday in the online version of Nature Medicine. The researchers were able to block infections similar to HIV in monkeys using their technique according to the study by Philip R. Johnson and colleagues at Children’s Hospital; Nationwide Children’s Hospital in Columbus hio; and the New England Primate Research Center in Boston. "We are bypassing the immune system" Johnson said yesterday. Instead of injecting weakened viral material into patients to activate the body’s natural response Johnson’s team tries to make the desired antibodies directly using a genetically altered "carrier" virus.
Controversy doesn’t derail stem cell progress
Whether similar physical forces play a role in the differentiation of other organ tissues is an open question Lensch says. However other papers out last week say some even more fundamental questions remain. “The link between stem and tumor cells in science is a very old one” says Paul Knoepfler of the University of California Davis School of Medicine in the. But no one talks about it much he adds even though understanding the link remains “an essential bridge to cross along the way” in someday turning embryonic cells into organ transplants. After all the most basic test of whether stem cells are truly “pluripotent” or able to turn into any type of tissue in signature embryonic cell fashion Knoepfler says is to inject them into a mouse and see if they grow into tumors.
Summer yoga opportunities in the Black Hills allow participants to …
Sioux Falls Argus Leader
The weekend will explore the Chakras and circular patterns of the wheel as a metaphor for healing set against the backdrop of the Badlands. Hike the Medicine Root trail and experience yoga with a view from the northern edge of the Badlands Wall. Participants will stay in a bed and breakfast and have an opportunity to try interactive workshops yoga classes and enjoy evening entertainment. The retreat includes meals accommodations and workshop materials and is $550 a person. Sign up by May 31st. In July a session on yoga hiking and rock climbing will take place in the Black Hills.
Personalized Cancer Treatment of the Future: RNAi Gene Silencers
The researchers at University of California San Diego School of Medicine have created a groundbreaking new delivery system for small interfering RNA or siRNA that penetrates cancer cell membranes and silences them through the RNA interference or RNAi pathway. Scientists have experimented with an individualized drug treatment using siRNAs for the past few years but ran into roadblocks when the negative charged siRNAs failed to penetrate the cell membranes. However researchers didn’t abandon the use of siRNAs because those double-stranded RNA molecules hold the key to the gene silencer RNAi pathways. The RNAi pathways hold great potential for knocking down cancer cells completely stopping their growth. Finally lead researcher Steven Dowdy PhD professor of cellular and molecular medicine discovered a siRNA delivery system binding siRNAs to a peptide transduction domain which has the ability to permeate cell membranes.
Inhibiting key protein may restore the balance between bone …
?These researchers have also stated that at present there may be certain treatments which may prevent any further bone loss but they may not increase bone mass. However the findings of this research indicate that the use of a drug which prevents the function of NF-kB may prove to be very helpful for this criterion. This research paper was published online on the Nature Medicine journal.
Framingham Heart Study follows the beat in new directions
Los Angeles Times
Pieces of those softened plaques are more likely to break away and clog the circulatory system. That’s when treatment is needed he says. To try to find a chemical warning sign BG Medicine will screen Framingham blood samples for about 1000 potential biomarkers. The company will be interested in substances that increased or decreased in the blood in the year leading up to a person’s heart attack. Muntendam expects to have some results by mid-2010. Another project announced in 2007 will sift through DNA for heart risk factors. Called the Single nucleotide polymorphism Health Association Resource or SHARe it includes data on 550000 genetic markers from 9300 Framingham participants.
Health utcomes Driving New Hospital Design
New York Times
A handrail next to the headboard of the bed will prevent falls. To prevent medication mix-ups and reduce the time nurses spend fetching drugs and supplies a small locked cabinet called the nurse server will contain only the medicine for the patient in that room. A sink near the door will allow nurses doctors and visitors to wash their hands before entering. The rooms will be angled to create sight lines from the hallway to the bed so nurses can easily see patients and vice versa. Acoustical materials will dampen noise and to encourage families to visit and spend time the rooms will be spacious and equipped with extra storage.
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