Key To Sonic Hedgehog Control Of Brain Development Found
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The News Review:

- Key To Sonic Hedgehog Control Of Brain Development Found
- Newly Formed Institute to Transform How Research Becomes Patient …
- Even Mild Sleep Apnea Increases Cardiovascular Risk
- MicroRNAs Make For Safer Cancer Treatments

Key To Sonic Hedgehog Control Of Brain Development Found
Science Daily (press release) 
28, 2008) — University of Pennsylvania School of Medicine researchers have discovered how the expression of the Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause brain malformations. The results appear online this month in Nature Genetics. See also: Health & MedicineBrain TumorBirth DefectsNervous SystemMind & BrainBrain InjuryIntelligenceNeuroscience Reference.
Related: Senior activities

Newly Formed Institute to Transform How Research Becomes Patient …
MarketWatch 
Barchi, MD, PhD,
President, Thomas Jefferson University. “Our
education plan is a key component–being
jointly developed with our partners. We’re
training a new cadre of scientists who will understand both the clinical
and translational side of medicine. ”

“Discoveries that could fuel groundbreaking,
real-world practices are limitless,”
emphasizes Robert Laskowski, MD, President and CEO, Christiana Care
Health System. “The DVICTS will have a direct
impact on the lives of people in Delaware, southeastern Pennsylvania and
southwestern New Jersey. ”

Joint projects of member institutions are already underway. Molecular
genetic markers are being developed to tailor and individualize cancer
therapy and research is being carried out on the use and applications of
proton beam therapy (housed at Jefferson) for cancer treatment.

Even Mild Sleep Apnea Increases Cardiovascular Risk
Science Daily (press release) 
The study will be published in the first issue for November of the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. "Only one out of approximately five subjects with [clinically defined OSA] complains of excessive daytime sleepiness in population studies," wrote Geraldo Lorenzi-Filho, M.

MicroRNAs Make For Safer Cancer Treatments
Science Daily (press release) 
The microRNAs destabilize the virus’s genome, making it impossible for the virus to run amok. The discovery is reported in the current issue of Nature Medicine. "Our findings demonstrate a new tool for molecular medicine that should also help allay concern over the use of viruses as a therapeutic delivery system," says Stephen Russell, M.

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