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- … | News for Dallas, Texas | Science, Health and Medicine |…
- Research Yields Clues to Diabetic Eye Disease
- Researchers seek way to help insomniacs get some shut-eye
- How to serve seniors?: There are too few geriatricians to care for…
- Engineered Magnetic Nanoparticles Image Small Tumors, Nanoparticles,…

… | News for Dallas, Texas | Science, Health and Medicine |…
Dallas Morning News - Dallas Morning News (subscription) - Jan 28, 2007
Those findings in a first-of-its-kind experiment also help explain why so many of the roughly 50 million who died in the Spanish flu pandemic were young and healthy. Based on what was seen in monkeys, the human victims’ strong immune systems probably were overstimulated, causing their lungs to rapidly fill with fluid. “Essentially people are drowned by themselves,” said University of Wisconsin virology professor Yoshihiro Kawaoka, lead author of a study published recently in the journal Nature. Scientists believe the results open a window into what could happen if the current bird flu in Asia morphs into a highly lethal strain that spreads easily among people. The 1918 virus was reconstructed with reverse genetics, relying on tissue from victims of the early-day flu pandemic. The virus is kept only in two labs where scientists are studying it: the U… “There was some surprise that it was that nasty,” said University of Washington virologist and study co-author Michael Katze. “It was the robustness of the immune system that helped victimize them. ” The virus is good at replicating itself, said Peter Palese, chairman of the microbiology department at Mount Sinai School of Medicine in New York. Its effect on the immune system “triggers what one refers to as a cytokine storm,” he said. Cytokines transmit messages among cells in the immune system. Palese wasn’t part of the study but has worked on the resurrected virus before.

Research Yields Clues to Diabetic Eye Disease
Lex 18 - Jan 28, 2007
The team concluded that a protein called carbonic anhydrase 1 (CA-1) causes leakage of retinal blood vessels, which contributes to the retinal swelling (diabetic retinal edema) often associated with advanced diabetic retinopathy. The study was published in the Jan. 28 online issue of Nature Medicine. The researchers also identified other proteins that may play a role in causing blood vessel leakage in the eyes. “By analyzing the protein composition in the human vitreous, we have identified a new group of molecules that may improve our understanding of the disease processes that contribute to diabetic retinopathy,” lead investigator Edward Feener, a researcher in Joslin’s section on vascular cell biology, director of Joslin’s Proteomics Core, and an assistant professor of medicine at Harvard Medical School, said in a prepared statement. “By studying the actions of these proteins in both the retina and the brain, we have shown that our findings may have broad relevance for neurovascular leakage and swelling,” Feener said. More information

The U.

Researchers seek way to help insomniacs get some shut-eye
Globe and Mail - Jan 28, 2007
They found that blocking brain receptors for orexin, a blood peptide, promoted sleep in rats, dogs and people, according to a paper in Sunday’s online issue of the journal Nature Medicine. com: Researchers seek way to help insomniacs get some shut-eye.

How to serve seniors?: There are too few geriatricians to care for…
Free with registration - Charlotte Observer - AccessMyLibrary.com - Jan 28, 2007
The shortage is only expected to worsen as 77 million aging baby boomers clamor for this kind of care in coming years. Anthony Caprio, who specializes in geriatrics at UNC Chapel Hill’s School of Medicine, sees a coming crisis: “a lot of older adults with chronic conditions. and a health care situation not prepared for it. ” Time to listen Chronic conditions — diabetes, rheumatoid arthritis, neuropathy.

Engineered Magnetic Nanoparticles Image Small Tumors, Nanoparticles,…
Nanotechwire.com - Jan 28, 2007
com - The online resource for Nano Technology And Research. In order to boost this signal, and improve the ability of MRI to detect the smallest tumors, researchers at Yonsei University in Seoul developed a new chemical method for making iron oxide nanoparticles that would enable them to more carefully control the physical and magnetic properties of these particles. As a result of this effort, described in a publication in the journal Nature Medicine, the investigators were able to detect small tumors implanted into mice. , who is also a member of Northwestern University’s Nanomaterials for Cancer Diagnostics and Therapeutics Center for Cancer Nanotechnology Excellence, led the team of investigators that explored how various chemical and physical parameters affect the magnetic signal produced by iron oxide nanoparticles. From these studies, the researchers were able to develop a synthetic technique, using high temperatures and organic solvents, that incorporated traces of manganese, cobalt, or nickel into iron oxide nanoparticles of diameters ranging from 6 to 12 nanometers.

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