The News Review:
- Scientists Show ‘Miracle’ Cancer Drug Gleevec Can Be Toxic To…
- Hastert May Challenge Order on Searches
- Preclinical Study Shows Chronic Stress Agitates Ovarian Cancer;…
- Study Links Stress to Poorer Outcome in Cancer
- Homegrown courage
Scientists Show ‘Miracle’ Cancer Drug Gleevec Can Be Toxic To…
Science Daily - Science Daily (press release) - Jul 24, 2006
Wilson Professor of Medicine at Jefferson Medical College of Thomas Jefferson University, has shown in studies in both mice and in heart cells in culture that Gleevec can cause heart failure. The results of the study, prompted by 10 patients with chronic myelogenous leukemia (CML) who developed severe congestive heart failure while taking Gleevec, appear July 23, 2006, in an advanced online edition of the journal Nature Medicine. "We found that the molecular target of the drug, the Abelson tyrosine kinase (ABL) protein, serves a maintenance function in cardiac muscle cells and is necessary for their health," Dr. "While the cancer is treated effectively, there will be some percentage of patients who could experience significant left ventricular dysfunction and even heart failure from this. "
"Gleevec is a wonderful drug and patients with these diseases need to be on it," he says.
Hastert May Challenge Order on Searches
Washington Post - Jul 24, 2006
Hogan denied Jefferson’s request to delay the investigation while the congressman appeals the judge’s earlier ruling that the office search was legal. * * *· A successful cancer-fighting drug may also damage the heart, although a researcher says leukemia patients who need Gleevec should not abandon it. Thomas Force, who teaches medicine at Jefferson Medical College of Thomas Jefferson University in Philadelphia, published his study in the online edition of the journal Nature Medicine, prompted by reports that 10 patients taking Gleevec for chronic myelogenous leukemia developed severe congestive heart failure. He said that doctors need to be aware of this and watch for symptoms. · SAN FRANCISCO — Sweltering heat was blamed for at least three deaths in Northern California, including a resident at a nursing home who died after the facility’s air conditioning failed. Triple-digit temperatures covered much of the Southwest. In California, the power grid manager warned that the state might declare an emergency for the second straight day because of soaring electricity use… Hogan denied Jefferson’s request to delay the investigation while the congressman appeals the judge’s earlier ruling that the office search was legal. * * *· A successful cancer-fighting drug may also damage the heart, although a researcher says leukemia patients who need Gleevec should not abandon it. Thomas Force, who teaches medicine at Jefferson Medical College of Thomas Jefferson University in Philadelphia, published his study in the online edition of the journal Nature Medicine, prompted by reports that 10 patients taking Gleevec for chronic myelogenous leukemia developed severe congestive heart failure. He said that doctors need to be aware of this and watch for symptoms. · SAN FRANCISCO — Sweltering heat was blamed for at least three deaths in Northern California, including a resident at a nursing home who died after the facility’s air conditioning failed. Triple-digit temperatures covered much of the Southwest. In California, the power grid manager warned that the state might declare an emergency for the second straight day because of soaring electricity use.
Preclinical Study Shows Chronic Stress Agitates Ovarian Cancer;…
Science Daily - Science Daily (press release) - Jul 24, 2006
Specifically, the researchers showed that stress hormones bind to receptors directly on tumor cells and, in turn, stimulate new blood vessel growth and other factors that lead to faster and more aggressive tumors. "This study provides a new understanding of how chronic stress and stress factors drive tumor growth," says Anil Sood, M. , associate professor of gynecologic oncology and cancer biology and director of ovarian cancer research.
Study Links Stress to Poorer Outcome in Cancer
Cancerpage.com - Jul 24, 2006
The study published in the journal Nature Medicine also found that a blood pressure drug reverses the effect. Studies aimed at finding out if stress causes cancer have not come up with a clear answer — and some have clearly ruled out any link between stressful life events, such as divorce or job loss, and later cancer. But many people believe stress can cause cancer. Anil Sood of The University of Texas M.
Homegrown courage
St. Petersburg Times - Jul 24, 2006
, she has written 10 books about women's lives during World War II. In American Heroine, she provides an introduction and extensive footnotes to give historical context to Virginia's story. "She never revealed the nature of her work in two months of interrogation in prison in France," says Litoff during a phone interview. "This was a woman who did the right thing. " *** Virginia was born in 1910 in Dayton, Ohio, the first of three children of Franklin and Edith Roush. The family moved to St. Petersburg when Virginia was 11 and lived in a farmhouse in a 10-acre citrus grove on the border of what is now Gulfport… Petersburg Junior College and graduated from Rollins College in 1935. She helped with her mother's small private school. Frank, the youngest, would be a doctor and, like his father, practice medicine in St. Petersburg after serving in the medical corps in the Philippines. As the middle child, Eleanora said, she was "very quiet. " Virginia was not. "She would say things that no one else dare say.
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