The News Review:
- New autoimmune treatment identified
- Abnormal Abeta - Protein Level in Human Brain Trigger Alzheimer’s…
- Scientists develop new method to monitor Alzheimer’s key protein
- Business digest
- Production of key Alzheimer’s protein monitored for first time in…
New autoimmune treatment identified
Gaffney Ledger - Gaffney Ledger (subscription) - Jun 26, 2006
Delovitch and his colleagues at Canada’s Robarts Research Institute, including Dr. Mi, reported in Nature Medicine that using alpha-GalCer to boost INKT cells and re-establish a healthy balance of good and bad immune cells prevented development of type I diabetes in an animal model for the disease. Mi and She say new INKT boosters likely are needed because the action of alpha-GalCer somehow depends on individual genetic architecture as well as other factors. Under certain conditions, the drug can help oiworsen an autoimmune disease by producing good oibad cytokines.
Abnormal Abeta - Protein Level in Human Brain Trigger Alzheimer’s…
MedIndia - Jun 26, 2006
Louis have developed the first safe and sensitive way to monitor the production and clearance rates of amyloid beta peptide (Abeta) in the human central nervous system. According to the authors, the new testing process opens a valuable window into the genesis of Alzheimer’s disease that, in addition to helping scientists better understand the origins of the condition, will likely help them improve its diagnosis and treatment. The scientists’ results will be published online on June 25 by Nature Medicine. High levels of Abeta in the brain are a hallmark of Alzheimer’s disease and believed to be a pivotal cause of the condition. Tests that measure Abeta levels in the cerebrospinal fluid have been available for some time. However, those fixed assessments of Abeta gave no indication of whether the flood of Abeta in patient’s brains came from an increase in the mechanisms that make the protein or a reduction in the processes that regularly clear it from the brain.
Scientists develop new method to monitor Alzheimer’s key protein
People's Daily Online - Jun 26, 2006
This new test technique may answer a longstanding question about the origins of Alzheimer’s disease: Do Alzheimer’s patients have high levels of the protein called amyloid beta peptide (Abeta) because they make too much of it, or because they can’t clear it from their brains quickly enough?
The test will open a valuable window into the genesis of Alzheimer’s disease that, in addition to helping scientists better understand the origins of the condition, will likely help them improve its diagnosis and treatment, according to researchers at the Washington University School of Medicine. These findings appeared in the June 25 online edition of the journal Nature Medicine. High levels of Abeta in the brain are a hallmark of Alzheimer’s disease and are believed to be a pivotal cause of the condition. Available testing measures can assess the Abeta levels in the patient’s cerebrospinal fluid, but they can give no indication of how Abeta accumulates in patient’s brains. Because Alzheimer’s symptoms take many years to develop, some researchers had assumed that the creation and clearance rates for Abeta were very slow. But the initial test of the new technique applied to six healthy volunteers suggests the opposite.
Business digest
St. Petersburg Times - Jun 26, 2006
* * * The Florida Cancer Institute has announced that Gail Shaw Wright, MD, has been appointed vice chair of the Department of Medicine at Morton Plant North Bay Hospital, New Port Richey. Wright is board certified in Internal Medicine and Medical Oncology. Her practice is limited to Medical Oncology and Hematology. Briefs Hannah-Bartoletta Homes and Morrison Homes were honored during the Pasco Building Association's 2006 Parade of Homes for their models at Wilderness Lake Preserve, Land O'Lakes, a master planned community in south central Pasco County. * * * Samuelsen Builders has opened a $1. 1-million estate model home featuring a stone accented elevation with columns flanking the double door entry in The Champions' Club, Trinity, an exclusive golf course community in southwest Pasco County… * * * Samuelsen Builders has opened a $1. 1-million estate model home featuring a stone accented elevation with columns flanking the double door entry in The Champions' Club, Trinity, an exclusive golf course community in southwest Pasco County. * * * Regional Medical Center Bayonet Point, Hudson, has received the American Heart Association's Get With The Guidelines-Coronary Artery Disease (GWTG-CAD) Excellence Award for the Nature Coast Division at the association's state annual meeting in Daytona Beach. * * * PAW Trucking has announced its expansion with the new parts and services division Fleet Tech. There was an official Chamber ribbon cutting at 6640 State Road 52, Bayonet Point. For more information, call Rick Wohlfiel (727) 862–5956. * * * State Farm recently presented a check to Pasco Safety Town to help cover construction costs for a new smoke building, which will be used to teach fire safety tips to children ranging in age from 5 to 9.
Production of key Alzheimer’s protein monitored for first time in…
People's Daily Online - Jun 26, 2006
The scientists report on Sunday on the online issue of journal Nature Medicine that via an intravenous drip, they give test subjects a form of the amino acid leucine that has been very slightly altered to label it. And they can monitor the production and clearance rate of Abeta through the labeled leucine. High levels of Abeta in the brain are a hallmark of Alzheimer’s disease and believed to be a pivotal cause of the condition. Tests that measure Abeta levels in the cerebrospinal fluid have been available for some time. However, those fixed assessments of Abeta gave no indication of whether the flood of Abeta in patient’s brains came from an increase in the mechanisms that make the protein or a reduction in the processes that regularly clear it from the brain.
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